Hello, Node.js is simply a better option than python if you wish to make your application real-time operations. Also Node.js is a better choice than python for server side development.

But let's get your problem now. For most ERP projects, Node.js is a better choice. Also, since you are already familiar with Node.js, continue with it. Personally, I think Node.js is way better than Django mainly because JS is the god of ERP projects. Java is a good counterpart though.