I always use Django on my projects. It is really easy and friendly fro the developer. It also comes with an inbuilt admin panel where you can manage all your models (tables), Django has a great authentication and authorization system, and it provides a great and powerful URL dispatcher, suitable for your needs. Furthermore, you can use a called django-pyodbc that is coded specifically for Microsoft SQL Server, and the SQL dialects for SQL Server ("T-SQL") and Access ("Access SQL"). However, I would not recommend using an Access DataBase with any web application's backend. Of course, it depends if you explicitly have Microsoft as your main tech stack.

Hope I helped you, and good luck with your project!