First of all, my experience using either Node.js with Express or NestJS is not wide. I liked NestJS due to it's similarity to Angular, so when you know Angluar and like TypeScript you are going to love NestJS, it will be instantly very familiar and easy to use, it's adds a good structure to the project out of the box and well, it uses TypeScript, which is a more structured language - it's good for scalability. As for performance concern s - NestJS is based on Node, it just brings Angular's modular structure to it, so the question is more about how is the additional layer influences the performance - I cannot answer that.