Node.js uses an event-driven, non-blocking I/O model that makes it lightweight and efficient, perfect for data-intensive real-time applications that run across distributed devices.
.NET is a developer platform made up of tools, programming languages, and libraries for building many different types of applications.
Rails is a web-application framework that includes everything needed to create database-backed web applications according to the Model-View-Controller (MVC) pattern.
Django is a high-level Python Web framework that encourages rapid development and clean, pragmatic design.
It is a web application framework with expressive, elegant syntax. It attempts to take the pain out of development by easing common tasks used in the majority of web projects, such as authentication, routing, sessions, and caching.