Waitress vs Owin: What are the differences?
Developers describe Waitress as "A production-quality pure-Python WSGI server *". It is meant to be a production-quality pure-Python WSGI server with very acceptable performance. It has no dependencies except ones which live in the Python standard library. It runs on CPython on Unix and Windows under Python 2.7+ and Python 3.4+. It is also known to run on PyPy 1.6.0 on UNIX. On the other hand, *Owin** is detailed as "A standard interface between .NET web servers and web applications". It is a standard for an interface between .NET Web applications and Web servers. It is a community-owned open-source project.
Waitress and Owin can be categorized as "Web Server Interface" tools.
Waitress and Owin are both open source tools. Waitress with 640 GitHub stars and 94 forks on GitHub appears to be more popular than Owin with 149 GitHub stars and 51 GitHub forks.