1. Deployment and Management: Cisco Umbrella is a cloud-based service that can be easily deployed and managed remotely without the need for physical servers, whereas ESET Endpoint Security requires on-premises installation and management.
2. Protection Scope: Cisco Umbrella provides DNS-layer security, preventing threats before they reach the network, while ESET Endpoint Security offers comprehensive endpoint protection with features like antivirus, firewall, and intrusion detection and prevention systems.
3. Scalability: Cisco Umbrella can easily scale up or down based on the organization's needs without significant hardware adjustments, while ESET Endpoint Security may require additional hardware or licenses for scalability.
4. Behavior-based Detection: ESET Endpoint Security uses behavior-based detection techniques to identify and block new, unknown threats on endpoints, providing proactive protection, whereas Cisco Umbrella primarily focuses on blocking threats at the DNS layer.
5. Platform Compatibility: ESET Endpoint Security is compatible with various operating systems, including Windows, macOS, and Linux, offering a comprehensive endpoint security solution for diverse environments, unlike Cisco Umbrella, which may have limitations on specific platforms.
6. Advanced Threat Intelligence Feeds: Cisco Umbrella leverages threat intelligence from Cisco Talos to provide up-to-date information on emerging threats, giving organizations better visibility and protection against sophisticated attacks, which may not be as prominently featured in ESET Endpoint Security.

In Summary, Cisco Umbrella primarily focuses on DNS-layer security and cloud-based deployment, while ESET Endpoint Security offers comprehensive endpoint protection with behavior-based detection and platform compatibility.