1. Routing: Gin Gonic uses a simple and fast multiplexer router, while Macaron employs a more feature-rich router that supports method overriding, session filtering, and subdomain routing, offering more flexibility in routing configurations.
2. Middleware: Gin Gonic provides a straightforward middleware functionality with global middleware support, whereas Macaron offers a comprehensive middleware stack with the ability to define middleware to specific routers, allowing for more fine-grained control over the middleware chain.
3. Validation: Gin Gonic does not have built-in validation support, requiring developers to use third-party libraries for input validation, while Macaron includes input validation and binding functionalities out of the box through its Form struct and validation engine, simplifying the validation process.
4. Configuration: Gin Gonic has a minimalistic configuration approach with basic settings, whereas Macaron has a more structured configuration system with support for configuration files, environment variables, default values, and runtime reloadability, facilitating easier configuration management.
5. Error Handling: Gin Gonic has a simple error handling mechanism that involves defining a custom error handler, whereas Macaron provides more sophisticated error handling with the ability to set different error handlers for different responses and supports custom error pages, improving error reporting and application usability.
6. Community Support: Gin Gonic has a larger community and a more active ecosystem with a wide range of third-party middleware, plugins, and tools compared to Macaron, which has a smaller community but focuses on robust and stable core functionality.

In Summary, Gin Gonic and Macaron differ in routing flexibility, middleware control, validation support, configuration management, error handling, and community support.