1. Deployment Options: McAfee Endpoint Protection offers both traditional on-premises deployment as well as cloud-based deployment options, providing flexibility to organizations based on their preferences and requirements. On the other hand, Tenable.sc is a cloud-based vulnerability management platform that eliminates the need for organizations to maintain their own on-premises infrastructure. This allows for easier and streamlined deployment, reducing the complexity and maintenance burden for organizations.

2. Feature Set: McAfee Endpoint Protection provides a comprehensive set of security features such as antivirus, anti-malware, firewall, intrusion prevention, and web control. It offers protection against a wide range of threats and ensures the security of endpoint devices. In contrast, Tenable.sc primarily focuses on vulnerability management, providing capabilities to identify, prioritize, and remediate vulnerabilities across an organization's IT infrastructure. It helps organizations in assessing and managing their security posture by actively scanning for vulnerabilities and providing detailed vulnerability reports.

3. Scalability: McAfee Endpoint Protection is designed to protect endpoint devices across the entire organization, including laptops, desktops, servers, and mobile devices. It can scale to support large enterprise environments with thousands of endpoints. On the other hand, Tenable.sc is primarily focused on vulnerability management and can scale to support organizations with extensive IT infrastructures, encompassing a large number of assets and systems. It provides the capability to manage and assess vulnerabilities at scale.

4. Integration Capabilities: McAfee Endpoint Protection integrates with other McAfee security products, such as McAfee ePolicy Orchestrator (ePO), to provide centralized management and reporting capabilities. It enables organizations to have a unified view of their security infrastructure and streamline security operations. Tenable.sc, on the other hand, offers integration capabilities with various third-party security tools, allowing organizations to aggregate vulnerability data from multiple sources and centralize it within the vulnerability management platform.

5. Reporting and Analytics: McAfee Endpoint Protection provides reporting and analytics capabilities to monitor the security posture of endpoint devices and track security incidents. It offers customizable dashboards and reports to provide insights into the overall security status. Tenable.sc offers advanced reporting and analytics features specifically focused on vulnerability management. It provides detailed vulnerability reports, visualizations, and analytics to help organizations prioritize and remediate vulnerabilities effectively.

6. Price and Licensing Model: McAfee Endpoint Protection follows a traditional software licensing model, where organizations need to purchase licenses for the endpoint devices they want to protect. The cost varies based on the number of licenses required. Tenable.sc, on the other hand, follows a subscription-based pricing model, where organizations pay for the number of assets they want to manage for vulnerability management. The cost is based on the organization's IT infrastructure size and the desired level of functionality.

In Summary, McAfee Endpoint Protection offers flexible deployment options, a comprehensive feature set, scalability for large enterprise environments, integration capabilities with other McAfee products, and reporting/analytics functionalities. On the other hand, Tenable.sc is a cloud-based vulnerability management platform with a focus on vulnerability assessment, scalability for extensive IT infrastructures, integration capabilities with third-party security tools, and advanced reporting/analytics features.