1. Key Difference 1: Language: Gin Gonic is a web framework built using Go, while Laravel is a web framework built using PHP. This difference in programming language affects the syntax, structure, and overall ecosystem of the frameworks. Developers familiar with either Go or PHP will have to adapt to the specific language conventions when working with Gin Gonic or Laravel, respectively.

2. Key Difference 2: Performance: Gin Gonic is known for its high performance due to its efficient routing and fast JSON encoding and decoding capabilities. On the other hand, while Laravel offers a rich set of features and an expressive syntax, it may have some performance overhead due to its reliance on the PHP interpreter and its extensive use of dynamic features.

3. Key Difference 3: Community Support: Laravel has a large and active community of developers, which has contributed to an extensive ecosystem of packages, documentation, and resources. Gin Gonic, being a relatively newer framework, has a smaller but growing community. This can impact the availability of support, resources, and third-party packages for developers working with these frameworks.

4. Key Difference 4: Convention over Configuration: Laravel follows the principle of "convention over configuration," providing sensible defaults and predefined structures for common tasks, which aids in rapid development. Gin Gonic, on the other hand, offers a more flexible and customizable approach, allowing developers to have more control over the application's configuration and structure.

5. Key Difference 5: Middleware: Middleware is a crucial component in web frameworks, allowing the processing of requests and responses before they reach the final route handler. In Gin Gonic, middleware functions as independent handlers that are executed sequentially, allowing fine-grained control over the request-response cycle. In Laravel, middleware is defined at the route level, providing a more centralized and declarative approach to handling middleware.

6. Key Difference 6: Database Support: Both Gin Gonic and Laravel provide support for working with databases. However, Laravel offers a more opinionated ORM (Object-Relational Mapping) called Eloquent, which simplifies database interactions and provides an expressive syntax for querying. Gin Gonic, being a minimalistic framework, does not include an ORM by default, but developers can choose and integrate their preferred database library or ORM.

In summary, the key differences between Gin Gonic and Laravel include the choice of programming language, performance characteristics, community support, approach to convention over configuration, middleware handling, and database support.