1. Customization Options: Plume offers a wider range of customization options compared to Write.as, allowing users to personalize their blog's appearance more extensively with themes, fonts, colors, and layout adjustments.

2. Collaborative Writing Features: Write.as has collaborative writing features such as real-time editing, commenting, and version history for users to work together on posts, while Plume focuses more on individual writing and editing capabilities.

3. Audience Interaction Tools: Write.as provides tools for interacting with the audience, such as embedded media, comments section, and share buttons, creating a more engaging experience for readers compared to Plume's focus on the writing experience itself.

4. Pricing Structure: Write.as offers a free basic plan with limited features and a paid subscription for advanced features, while Plume operates on a donation-based model, allowing users to contribute based on their usage and support for the platform.

5. Community Integration: Plume emphasizes integration with federated networks and decentralized platforms, enabling users to connect with a broader online community, while Write.as focuses on building a self-contained blogging platform for individual and collaborative writing needs.

6. Mobile Accessibility: Write.as has dedicated mobile apps for iOS and Android devices, providing a streamlined user experience on smartphones and tablets, whereas Plume may require more optimization for mobile browsing and posting.

In Summary, Plume and Write.as differ in customization options, collaborative writing features, audience interaction tools, pricing structure, community integration, and mobile accessibility.