Factually talking about systems, we gotta make two bold headlines about each one: Bootstrap has been around for a while, has a vast community and much probably will not be gone in a while. Tailwind in the other hand, is the trendy framework starting from the past year. Referring to UI, I really prefer Tailwind, however I can't ignore the fact that a lot of libraries that emerged felt short in the end after a few years (a point where Bootstrap kept his status).

You are able to use both them together but I advise you — it will be a mess. And you gotta hope that you won't have any kind of conflicts between class naming and other general styling.

My recommendation would be to use one and only one. Perhaps rebuild the UI with a specific framework in mind, otherwise you will start to workaround things of both frameworks to contradict each other - and your team (if you work with one) will hate you.

You might have heard about bootstrap 5. Bootstrap is now totally jQuery free. i have tried foundation and bulma too. but eventually fall again for bootstrap, as it is most convenient and stable. i use bootstrap with less or sass.

I use both of these regularly. If you're going to have to use Bootstrap due to your js dependencies, stick with Bootstrap. I actually prefer Tailwind, but trying to use both of them and make them "play nice" feels like making things more complex with no real benefit.

EDIT: Sorry for the late response, I just noticed how old this is. StackShare sent me this in an email for some reason so I assumed it was relatively fresh.

Hey Sai, My thoughts on UIkit - It's beautiful, fast, and it has good animation too. Why would I choose it ? Nothing other than giving the internet a new look .

My thoughts on Bootstrap - it's beautiful, if used well. It's very fast and has clean class naming convention unlike Uikit. Why I would choose it ? It's been tested and trusted, I can find a whole lot of resources and a community around it. Also with the type of project you working on I bet Bootstrap would do the job .

Now, considering Tailwind, it's seen as a classic, simple-to-set-up tool with clean utilities. I wouldn't think of tailwind the way I would to Bootstrap or UIkit. What do I mean ? Tailwind is more like a tool set to create your own design flow. Tailwind allows you to build unique design elements, offering you a level of customization that may be unmatched by the other frameworks.

My final thoughts.

If you have the time , setup and use tailwind it will give you a great chance when it comes to customization and performance.

I'm a big proponent of Tailwind and I personally use it whenever I get the chance, mostly because it's not really a UI-kit, but it sounds like in this case a UI-kit like Bootstrap with pre-defined components is more what you are looking for. Bootstrap is (relatively) extendable and overridable and makes it really simple to make a decent looking UI using a handful of pre-defined classes, whereas with Tailwind you configure the classes and create your own components. My main reason for replacing Bootstrap in my workflow is that it feels like the component creation has become so abstracted from the developer that any meaningful customization becomes a chore, resulting in many websites having the generic "Bootstrap-look". Nonetheless, it is effective for creating a pleasant and responsive UI. Though, I don't have any experience with UIkit.