1. Template Engine: The main difference between Blade and Twig is the template engine they use. Blade is the default templating engine used in Laravel, a PHP framework, while Twig is the default templating engine used in Symfony, a PHP framework.
2. Syntax: Blade uses more concise and familiar PHP-like syntax, while Twig uses its own syntax, which is inspired by the Python programming language. For example, in Blade, variables are enclosed in double curly braces ({{ }}, while in Twig, variables are enclosed in double curly braces with an additional percentage sign ({{ % }}).
3. Whitespace Control: Blade allows developers to control the whitespace between HTML tags, making it easy to format the output. Twig, on the other hand, automatically strips unnecessary whitespace, which can sometimes result in cleaner-looking code.
4. Extensibility: Twig provides a rich set of built-in tags, filters, and functions that can be easily extended and customized. Blade, on the other hand, has a simpler syntax and a more limited set of built-in functionality.
5. Integration with Frameworks: Blade is tightly integrated with the Laravel framework, making it the preferred choice for Laravel developers. Twig, on the other hand, can be used with a variety of PHP frameworks, including Symfony, Drupal, and Slim.
6. Error Reporting: Blade provides detailed error messages and line numbers when there are syntax errors or issues with template rendering. Twig also provides helpful error messages but may not be as detailed or specific as Blade's error reporting.

In Summary, Blade and Twig are both powerful templating engines used in PHP frameworks. Blade offers a more concise syntax and is tightly integrated with Laravel, while Twig provides a rich set of features and can be used with multiple PHP frameworks.