1. Networking: Docker Machine allows you to create and manage multiple Docker hosts on local or cloud infrastructures, while Smith focuses on simplifying the process of managing Docker containers and services running on a single host.

2. Scope: Docker Machine is more suitable for managing large-scale infrastructures with multiple hosts, while Smith is designed for smaller projects where a single Docker host suffices.

3. Functionality: Docker Machine provides tools for creating, running, and managing Docker hosts on various environments, while Smith focuses on managing containers, services, and networks on a single host.

4. User Interface: Docker Machine requires users to interact with the command line interface for managing Docker hosts, while Smith offers a graphical web-based interface for managing containers and services.

5. Automation: Docker Machine supports automation and scripting for deploying Docker hosts, while Smith focuses on simplifying manual management tasks on a single host.

6. Integration: Docker Machine integrates seamlessly with Docker Swarm for orchestration and scaling, while Smith focuses on providing a simple, user-friendly interface for managing Docker containers and services.

In Summary, Docker Machine is suited for managing multiple Docker hosts on various infrastructures, while Smith simplifies the management of containers and services on a single host.