1. Integration Flexibility: Adyen offers more flexibility with its robust APIs and SDKs, allowing for seamless integration with various platforms and custom applications. On the other hand, 2checkout may have limited integration options, potentially causing complications for businesses with specific requirements.

2. Global Payment Methods: Adyen supports a wide range of global payment methods, catering to diverse customer needs from different regions. In comparison, 2checkout might have a more limited selection of payment methods available, possibly resulting in lower conversion rates for international transactions.

3. Risk Management Capabilities: Adyen provides advanced risk management tools and fraud prevention features to safeguard businesses from potential threats and chargebacks. Meanwhile, 2checkout may have a more basic risk management system, which could leave businesses vulnerable to fraudulent activities and financial losses.

4. Pricing Structure: Adyen offers a transparent pricing model with competitive rates and clear fees, helping businesses plan their budget effectively. Conversely, 2checkout's pricing structure may include hidden charges or higher transaction fees, impacting the overall cost for businesses using their services.

5. Payout Frequency: Adyen provides faster payout cycles, allowing businesses to access their funds quicker and improve cash flow management. However, 2checkout may have longer payout periods, potentially causing delays in receiving payments and affecting the financial operations of businesses.

In Summary, Adyen stands out for its integration flexibility, global payment methods, advanced risk management capabilities, transparent pricing structure, and faster payout frequency compared to 2checkout.