Deepdesk

If you want framework-agnostic code, Django is really not the right framework for you. Its large ORM layer, heavy use of middleware, and reliance on class inheritance, will make migrating to another framework very painful. For more freedom and control I would recommend Flask, or even better FastAPI.

At the same time, it seems DDD has nothing to do with using other libraries or not.

Either way, whatever framework you choose, remember the golden rule: Don’t Fight The Framework.

Since the course is in Python, a Python web framework seems like a logical choice. Django is a good option, but Flask and FastAPI are far more lightweight than Django, and great for quickly adding an API on top of your ML/NLP code. Django has its merits, especially the generated admin interface, but requires a lot of boilerplate code.