1. License: Axure requires a one-time purchase of a software license, whereas Moqups offers a subscription-based payment model. This difference in pricing structure can appeal to different user preferences based on their financial constraints.

2. Collaboration Features: Moqups has built-in collaboration features that allow multiple users to work on a project simultaneously in real-time, whereas Axure requires additional plugins or third-party tools to enable collaborative work. This difference can significantly impact team productivity and communication during the design process.

3. Prototyping Capabilities: While both Axure and Moqups offer prototyping features, Axure provides more advanced interactive capabilities and dynamic content options for creating highly functional prototypes. In contrast, Moqups is more focused on static wireframes and basic interactions, making it suitable for simpler projects that do not require complex simulations.

4. Platform Accessibility: Axure is a desktop-based application available for Windows and macOS, offering offline access to projects. On the other hand, Moqups is a web-based tool accessible through a browser, allowing users to work on designs from any device with an internet connection. This distinction in platform accessibility can influence user preferences based on their need for mobility and convenience.

5. Learning Curve: Axure has a steeper learning curve due to its robust feature set and complex interface, requiring more time and effort to master. In contrast, Moqups is known for its user-friendly interface and intuitive design tools, making it a more accessible option for beginners or less experienced designers. This difference in learning curve can impact the adoption rate and usability of the tools among different user groups.

6. Integration Options: Axure offers more extensive integration options with other design tools, such as Sketch and Adobe XD, allowing for seamless workflows and file imports/exports. Moqups, on the other hand, has limited integration capabilities, which can be a drawback for users who heavily rely on third-party tools for their design processes. This difference in integration options can affect the overall efficiency and compatibility of the design workflow.

In Summary, Axure and Moqups differ in terms of licensing, collaboration features, prototyping capabilities, platform accessibility, learning curve, and integration options, catering to varying user needs and preferences in the design process.